从大鼠下丘脑对一种5700道尔顿形式的P物质样免疫反应性进行表征及部分纯化。
Characterization and partial purification of a 5,700 dalton form of substance P-like immunoreactivity from the rat hypothalamus.
作者信息
Harmar A J, Armstrong A, Lee C M, Emson P C
出版信息
Brain Res. 1984 Dec 10;323(2):342-4. doi: 10.1016/0006-8993(84)90310-x.
PMID:6084540
Abstract
Analysis of rat hypothalamic extracts by gel filtration and HPLC revealed the presence of a form of substance P-like immunoreactivity with a molecular weight of approximately 5,700 (6k-SP). 6k-SP is probably an N-terminally extended form of substance P; the peptide may be an intermediate in SP biosynthesis, or may function as a biologically active peptide in its own right.
摘要
通过凝胶过滤和高效液相色谱法对大鼠下丘脑提取物进行分析，结果显示存在一种分子量约为5700的P物质样免疫反应性形式（6k-SP）。6k-SP可能是P物质的N端延伸形式；该肽可能是P物质生物合成的中间体，或者本身可能作为一种生物活性肽发挥作用。
Zotero 插件