Buxeraud J, Absil A C, Raby C
J Pharm Sci. 1984 Dec;73(12):1687-90. doi: 10.1002/jps.2600731205.
Molecular interactions between iodine and disulfiram, clomethiazole, and tolnaftate were investigated by electron spectroscopy. Iodine forms charge transfer complexes with these molecules, with 1:1 stoichiometry and of the n-sigma type. The formation constants were compared with those obtained with antithyroid molecules. Only disulfiram appears to have any effect on the intrathyroid cycle of iodine.
通过电子能谱研究了碘与双硫仑、氯美噻唑和托萘酯之间的分子相互作用。碘与这些分子形成电荷转移络合物,化学计量比为1:1,属于n-σ型。将形成常数与用抗甲状腺分子得到的常数进行了比较。只有双硫仑似乎对甲状腺内的碘循环有任何影响。