Link M, Kemnitz P
Zentralbl Gynakol. 1976;98(11):671-81.
Cyclic alterations of the endometrium are known for certain, but similar processes of the mucous membrane of the uterine cervix are vague. In pregancy there is a considerable increase in secretion. The epithelium of surface and glands becomes stratified and the nuclei of cylindrical epithelial cells withdraw from the base of the cells and often originate retronuclear vacuols. From these vacuols one has to distinguish so-called subcylindrical vacuols which only appear during pregnancy. They are seen between epithelium and basal membrane. Electron microscopical investigations show the vacuols lined partly by atrophical partly bysecretory cylindrical cells. Histochemically the contents of the vacuols are similar to the cytoplasm of cylindrical cells and the contents of glands. These alterations of the cervical mucous membrane are dependent on hormonal stimulation and in conclusion it must be possible to demonstrate the hormonal situation andits disturbances by investigations of the mucous membrane of the cervix uteri.
子宫内膜的周期性变化是确定无疑的，但其子宫颈黏膜的类似变化却尚不明确。妊娠期间分泌物会显著增加。表面上皮和腺上皮会变成复层，柱状上皮细胞的细胞核从细胞基部退缩，常常产生核周空泡。必须将这些空泡与仅在妊娠期间出现的所谓亚柱状空泡区分开来。它们见于上皮与基底膜之间。电子显微镜检查显示，这些空泡部分由萎缩的柱状细胞衬里，部分由分泌性柱状细胞衬里。组织化学研究表明，空泡内容物与柱状细胞的细胞质以及腺体的内容物相似。子宫颈黏膜的这些变化依赖于激素刺激，总之，通过对子宫颈黏膜的研究必定有可能显示激素状况及其紊乱情况。
