Philipp E
Zentralbl Gynakol. 1977;99(10):577-89.
Electron microscopical investigations of the cylindrical epithelium of the human cervix uteri demonstrate in the cytoplasm of the secretory cells tubular precoursers of secretory granules which become granular during the differentiation process of the epithelium. In the seventh fetal month mucous granules occasionally show a confluence. In the eights fetal month, typical cuboidal reserve cells are detected near the basis of the epithelium between the secretory cells and the ciliar cells. Under maximal increase of the rough endoplasmatical reticulum the production of secretory granules proceeds. By mitosis a functional adaptation of the epithelium to the growth of the cervical canal is achieved. The differentiation of the endocervical epithelium is nearly finished in the middle of the ninth month. At this time, merocrine extrusion processes become evident.
对人类子宫颈柱状上皮的电子显微镜研究表明，在分泌细胞的细胞质中存在分泌颗粒的管状前体，这些前体在上皮细胞的分化过程中变成颗粒状。在胎儿第七个月时，黏液颗粒偶尔会出现融合。在胎儿第八个月时，在上皮基部、分泌细胞和纤毛细胞之间检测到典型的立方形储备细胞。在粗面内质网最大限度增加的情况下，分泌颗粒开始产生。通过有丝分裂，上皮细胞实现了对宫颈管生长的功能适应。宫颈内膜上皮的分化在第九个月中旬基本完成。此时，局部分泌排出过程变得明显。
