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多巴胺和P物质注入对巴甫洛夫和海登海因袋犬胃酸分泌的影响。

Effects of dopamine and substance P infusion on gastric acid secretion in Pavlov and Heidenhain pouched dogs.

作者信息

Ogoshi K, Mitomi T, Nakamura S, Haruyama K, Yoshino K

出版信息

Tokai J Exp Clin Med. 1984 Aug;9(3):183-90.

PMID:6085704
Abstract

The effects of dopamine and Substance P infusion on gastric secretion have been evaluated in Pavlov and Heidenhain pouched dogs. Basal gastric acid secretion was significantly inhibited during both dopamine and Substance P infusion in conscious pavlov pouched dogs. Substance P inhibited tetragastrin-stimulated gastric secretion much more than dopamine. These data suggest that the effects of dopamine and Substance P on gastric secretion depend on the vagal condition.

摘要

在巴甫洛夫袋状胃和海登海因袋状胃的犬类中,已评估了多巴胺和P物质输注对胃液分泌的影响。在有意识的巴甫洛夫袋状胃犬中,多巴胺和P物质输注期间基础胃酸分泌均受到显著抑制。P物质比多巴胺更能抑制四肽胃泌素刺激的胃液分泌。这些数据表明,多巴胺和P物质对胃液分泌的影响取决于迷走神经状况。

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