Ogoshi K, Mitomi T, Nakamura S, Haruyama K, Yoshino K
Tokai J Exp Clin Med. 1984 Aug;9(3):183-90.
The effects of dopamine and Substance P infusion on gastric secretion have been evaluated in Pavlov and Heidenhain pouched dogs. Basal gastric acid secretion was significantly inhibited during both dopamine and Substance P infusion in conscious pavlov pouched dogs. Substance P inhibited tetragastrin-stimulated gastric secretion much more than dopamine. These data suggest that the effects of dopamine and Substance P on gastric secretion depend on the vagal condition.
在巴甫洛夫袋状胃和海登海因袋状胃的犬类中,已评估了多巴胺和P物质输注对胃液分泌的影响。在有意识的巴甫洛夫袋状胃犬中,多巴胺和P物质输注期间基础胃酸分泌均受到显著抑制。P物质比多巴胺更能抑制四肽胃泌素刺激的胃液分泌。这些数据表明,多巴胺和P物质对胃液分泌的影响取决于迷走神经状况。