Kamenskiĭ V A, Naraev S S, Borisov A S
Zh Mikrobiol Epidemiol Immunobiol. 1976 Apr(3):87-91.
The authors analyzed epidemiological and clinical peculiarities of infectious hepatitis in children aged under 11 years in conditions of mass-gamma-globulin prophylaxis in microdoses the last 5 years in Voronezh. It appeared that the incidence of the disease fell and that its clinical course became milder. In connection with reduction of the incidence of infectious hepatitis in the age group of under 10 years, the incidence of the disease was relatively higher in children aged from 10 to 14 years, with a tendency to levelling-out the periodic autumno-winter elevations among preschool children. Introduction of decreased gamma-globulin dose for hepatitis prophylaxis led to a lesser expenditure of the preparation and thus permitted to vaccinate more children.
作者分析了沃罗涅日过去5年在小剂量大规模丙种球蛋白预防条件下11岁以下儿童感染性肝炎的流行病学和临床特点。结果显示，该病发病率下降，临床病程变轻。随着10岁以下年龄组感染性肝炎发病率的降低，10至14岁儿童的发病率相对较高，且学龄前儿童秋冬季节性发病率升高的趋势趋于平稳。采用降低剂量的丙种球蛋白进行肝炎预防，减少了制剂用量，从而能够为更多儿童接种疫苗。
