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[考虑发病率预后改进系统性γ球蛋白预防病毒性肝炎的策略]

[Improvement in the tactics of systematic gamma globulin prevention of viral hepatitis taking the morbidity prognosis into account].

作者信息

Aleinik M D, Krivitskaia V S, Riabikova T F, Grinshtein E A, Makarevich I K

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1979 Jan(1):59-64.

PMID:85395
Abstract

On the example of 4 cites of the RSFSR under conditions of expected epidemic threat a possibility was shown of directed influence on the viral hepatitis A epidemic process of preseasonal gamma-globulin prophylaxis conducted in 90% of "organized" children, aged from 1 to 12 years. The dose used was 0.75 ml of a 10% preparation. The method of Gorky Institute of Epidemiology and Microbiology was used to prognosticate the morbidity. It is recommended to improve the tactics of preseasonal gamma-globulin prophylaxis with consideration to the data of the viral hepatitis prognosis.

摘要

以俄罗斯苏维埃联邦社会主义共和国4个城市为例,在预期有疫情威胁的情况下,对90%年龄在1至12岁的“组织起来”的儿童进行季节性前丙种球蛋白预防,结果显示了对甲型病毒性肝炎流行过程的定向影响。使用的剂量是10%制剂0.75毫升。采用高尔基流行病学和微生物学研究所的方法预测发病率。建议根据病毒性肝炎预后数据改进季节性前丙种球蛋白预防策略。

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