Aleinik M D, Krivitskaia V S, Riabikova T F, Grinshtein E A, Makarevich I K
Zh Mikrobiol Epidemiol Immunobiol. 1979 Jan(1):59-64.
On the example of 4 cites of the RSFSR under conditions of expected epidemic threat a possibility was shown of directed influence on the viral hepatitis A epidemic process of preseasonal gamma-globulin prophylaxis conducted in 90% of "organized" children, aged from 1 to 12 years. The dose used was 0.75 ml of a 10% preparation. The method of Gorky Institute of Epidemiology and Microbiology was used to prognosticate the morbidity. It is recommended to improve the tactics of preseasonal gamma-globulin prophylaxis with consideration to the data of the viral hepatitis prognosis.
以俄罗斯苏维埃联邦社会主义共和国4个城市为例，在预期有疫情威胁的情况下，对90%年龄在1至12岁的“组织起来”的儿童进行季节性前丙种球蛋白预防，结果显示了对甲型病毒性肝炎流行过程的定向影响。使用的剂量是10%制剂0.75毫升。采用高尔基流行病学和微生物学研究所的方法预测发病率。建议根据病毒性肝炎预后数据改进季节性前丙种球蛋白预防策略。
