Huertas Mora R A, Larrodera López L, Gómez Matobella I, Cortes Funes H
Rev Esp Oncol. 1984;31(2):321-30.
Alpha-fetoprotein (AFP) and the beta subunit of human chorionic gonadotropin (BHCG) were determined in 64 cases of testicular germinal tumors. Pure seminomas do not produce either AFP or BHCG, endodermal sinus tumors always produce AFP and never BHCG. Testicular germinal tumors may produce BHCG (44.4 per 100) and AFP (33.3 per 100), one or both at a time. There is a significant correlation between the amount of BHCG and AFP on the one hand, and tumor size and tumor dissemination on the other. When therapy is effective, BHCG and AFP become negative, while they remain positive in case of incomplete tumor removal or turn again to positive in case of relapse.
对64例睾丸生殖细胞瘤患者测定了甲胎蛋白（AFP）和人绒毛膜促性腺激素β亚基（βHCG）。纯精原细胞瘤既不产生AFP也不产生βHCG，内胚窦瘤总是产生AFP而从不产生βHCG。睾丸生殖细胞瘤可能产生βHCG（每100例中有44.4例）和AFP（每100例中有33.3例），一次产生一种或两种。一方面，βHCG和AFP的量与肿瘤大小和肿瘤播散之间存在显著相关性。当治疗有效时，βHCG和AFP变为阴性，而在肿瘤切除不完全的情况下它们仍为阳性，或在复发时再次转为阳性。
