Albaugh J S, Keeffe E B, Krippaehne W W
Dig Dis Sci. 1984 Aug;29(8):762-7. doi: 10.1007/BF01312952.
A 24-year-old man with hepatocellular carcinoma presented with recurrent obstructive jaundice caused by bile duct invasion and distal migration of necrotic tumor fragments. After resection of an isolated left lobe tumor, he was well for 2 years until he again presented with obstructive jaundice caused by necrotic tumor and clot in the common bile duct. Analysis of his tumor revealed the fibrolamellar histologic variant of hepatocellular carcinoma. This case is unique in that the hepatocellular carcinoma was of the fibrolamellar variant and presented both initially and when recurrent 2 years later with obstructive jaundice caused by invasion of the common bile duct.
一名24岁的肝细胞癌男性患者，因胆管受侵及坏死肿瘤碎片向远端迁移而出现反复梗阻性黄疸。在切除孤立的左叶肿瘤后，他情况良好达2年，直至再次因胆总管内坏死肿瘤及血凝块而出现梗阻性黄疸。对其肿瘤的分析显示为肝细胞癌的纤维板层组织学变异型。该病例的独特之处在于，肝细胞癌为纤维板层变异型，初次发病及2年后复发时均表现为因胆总管受侵所致的梗阻性黄疸。
