Braithwaite A W, Lejeune S, Naora H
DNA. 1984 Jun;3(3):223-30. doi: 10.1089/dna.1.1984.3.223.
The DNAs of human adenovirus types 2 and 5 (Ad2, Ad5) hybridize to genomic DNAs from human and chicken tissue. The pattern of Southern blot hybridization to genomic DNA digested with Eco RI suggests that sequences homologous to cloned Ad2 DNA are reiterated in genomic DNA. This was confirmed by liquid hybridization which shows that the hybrids have a low C0t 1/2 value. Finally, we show that total genomic human DNA probes hybridize to short fragments of adenoviral DNA in early-region genes near the ends of the viral genome.
人腺病毒2型和5型（Ad2、Ad5）的DNA与来自人和鸡组织的基因组DNA杂交。用Eco RI消化基因组DNA后进行的Southern印迹杂交模式表明，与克隆的Ad2 DNA同源的序列在基因组DNA中是重复的。液相杂交证实了这一点，其表明杂交体具有低的C0t 1/2值。最后，我们表明，总的人基因组DNA探针与病毒基因组末端附近早期区域基因中的腺病毒DNA短片段杂交。
