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[IgM型甲型肝炎病毒抗体的证实与出现]

[Demonstration and occurrence of IgM-type hepatitis A viral antibodies].

作者信息

Scheiermann N, Kuwert E

出版信息

Dtsch Med Wochenschr. 1984 Jun 8;109(23):902-6. doi: 10.1055/s-2008-1069294.

DOI:10.1055/s-2008-1069294
PMID:6086261
Abstract

Hepatitis-A antibody of the IgM class can be demonstrated in serum by radio-immunoassay quickly, relatively cheaply and simply. The diagnosis of fresh or recent hepatitis-A virus infection can be made from a single serum sample in a single test. Epidemiological analysis of the positive findings obtained in 1981 gave the following results: 1. Hepatitis-A is, in Germany, largely a disease of young adults, with an average age of 24 years. But cases still occurred above the age of 50.2. Among foreigners positive results were obtained already in children (average age 7 years). 3. While in foreigners the disease predominantly occurred in the last four months of the year, among Germans the distribution had three peaks related causally to the holiday months of April, July and October.

摘要

通过放射免疫测定法,可在血清中快速、相对廉价且简便地检测出IgM类甲型肝炎抗体。仅通过一次检测中的一份血清样本,就能诊断出近期感染甲型肝炎病毒的情况。对1981年获得的阳性结果进行的流行病学分析得出以下结果:1. 在德国,甲型肝炎主要是年轻人的疾病,平均年龄为24岁。但50岁以上也有病例发生。2. 在外国人中,儿童(平均年龄7岁)就已出现阳性结果。3. 外国人中的发病主要集中在一年中的最后四个月,而德国人中的发病分布有三个高峰,分别与4月、7月和10月的节假日月份有因果关系。

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1
[Demonstration and occurrence of IgM-type hepatitis A viral antibodies].[IgM型甲型肝炎病毒抗体的证实与出现]
Dtsch Med Wochenschr. 1984 Jun 8;109(23):902-6. doi: 10.1055/s-2008-1069294.
2
A "reverse" solid-phase radio-immuno-assay for IgM-antibodies to hepatitis A virus.一种用于检测甲型肝炎病毒IgM抗体的“反向”固相放射免疫测定法。
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