Kaplan E, Shapley R
Exp Brain Res. 1984;55(1):111-6. doi: 10.1007/BF00240504.
While recording extracellularly from single neurons in the Lateral Geniculate Nucleus (LGN) of cats and monkeys, one often observes, in addition to action potentials, smaller and slower potentials which have been called 'S Potentials' (Bishop et al. 1962). Injection of the sodium channel blocker tetrodotoxin (TTX) into the eye of the cat causes spontaneous and light evoked S potentials to disappear. However, electrical stimulation of ganglion cells axons at the optic chiasm still elicits S potentials. Previous studies have shown that retinal ganglion cell impulses elicit S potentials. Our results prove that ganglion cell impulses are the ONLY source of these potentials; therefore, one can use them as a measure of ganglion cell input to the LGN.
在对猫和猴子的外侧膝状体核（LGN）中的单个神经元进行细胞外记录时，除了动作电位外，人们还经常观察到一些较小且较慢的电位，这些电位被称为“S电位”（Bishop等人，1962年）。向猫的眼睛注射钠通道阻滞剂河豚毒素（TTX）会导致自发和光诱发的S电位消失。然而，在视交叉处对视神经节细胞轴突进行电刺激仍能引发S电位。先前的研究表明，视网膜神经节细胞的冲动会引发S电位。我们的结果证明，神经节细胞的冲动是这些电位的唯一来源；因此，人们可以将它们用作衡量神经节细胞向LGN输入的指标。
