中性粒细胞减少宿主中的厌氧菌感染：多粘菌素的抗内毒素作用
Anaerobic infection in the neutropenic host: anti-endotoxin effect of polymyxin.
作者信息
Bannatyne R M, Cheung R
出版信息
Anticancer Res. 1984 May-Jun;4(3):169-70.
PMID:6087717
Abstract
The neutropenic mouse model of endotoxin-associated anaerobic sepsis was used to evaluate the anti-endotoxic effect of polymyxin. Administered as two spaced doses after lethal challenge with Bacteroides fragilis polymyxin produced a statistically significant protective effect.
摘要
采用内毒素相关厌氧败血症的中性粒细胞减少小鼠模型来评估多粘菌素的抗内毒素作用。在用脆弱拟杆菌进行致死性攻击后，分两次间隔给药，多粘菌素产生了具有统计学意义的保护作用。
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