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[口蹄疫病毒的电特性]

[Electrical properties of the foot-and-mouth disease virus].

作者信息

Ponomarev A P, Molchanova A I, Uziumov V L

出版信息

Nauchnye Doki Vyss Shkoly Biol Nauki. 1984(6):18-23.

PMID:6087939
Abstract

It has been shown that the electron microscopy method can be used for characteristics of the electric properties of foot-and-mouth disease virus. The appearance of simultaneous positive and negative staining during the negative staining of virus preparations with 3-4% PTV solution shows the presence of full virions of constant poles designated as positively and negatively stained areas of protein coat surface. The lateral orientation of virions on the film at routine conditions of preparation and the possibility of virion orientation on the film in the external electrical field allow to characterize the full virions as electric dipoles. It has been suggested that there is a relationship between a virus structure and the character of its electric properties.

摘要

已经表明,电子显微镜方法可用于口蹄疫病毒电特性的表征。在用3-4%磷钨酸(PTV)溶液对病毒制剂进行负染色时,同时出现正染色和负染色的现象表明存在具有恒定极性的完整病毒粒子,这些极性区域被指定为蛋白质衣壳表面的正染色和负染色区域。在常规制备条件下,病毒粒子在膜上的横向取向以及在外部电场中病毒粒子在膜上取向的可能性,使得可以将完整病毒粒子表征为电偶极子。有人提出病毒结构与其电特性之间存在关联。

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