Greist A, Einhorn L H, Williams S D, Donohue J P, Rowland R G
J Clin Oncol. 1984 Sep;2(9):1025-7. doi: 10.1200/JCO.1984.2.9.1025.
Patients with testicular cancer who have disseminated disease at presentation do not always undergo orchiectomy for diagnosis of staging before initiation of chemotherapy. Between October 1978 and November 1982 orchiectomy was performed following cisplatin combination chemotherapy in 20 patients with disseminated germ cell tumors. There were three patients with residual carcinoma in the removed testis and six patients with teratoma. Therefore, in patients with evidence of a primary testicular neoplasm that was not resected initially, orchiectomy should be performed after chemotherapy. Furthermore, the testis may be a sanctuary site for germ cell malignancies during systemic treatment.
初诊时已有播散性病变的睾丸癌患者在开始化疗前并不总是进行睾丸切除术以用于诊断分期。1978年10月至1982年11月期间，20例播散性生殖细胞肿瘤患者在接受顺铂联合化疗后进行了睾丸切除术。切除的睾丸中有3例残留癌，6例有畸胎瘤。因此，对于有原发性睾丸肿瘤证据但最初未切除的患者，应在化疗后进行睾丸切除术。此外，在全身治疗期间，睾丸可能是生殖细胞恶性肿瘤的一个庇护所。
