恶性生殖细胞肿瘤治疗后的第二原发癌。
Second cancer after treatment of malignant germ-cell tumors.
作者信息
Fosså S D, Wanderås E H, Heimdal K
机构信息
Department of Medical Oncology and Radiotherapy, Norwegian Radium Hospital, Oslo.
出版信息
World J Urol. 1994;12(3):151-4. doi: 10.1007/BF00192277.
Patients cured of a malignant germ-cell tumor are at a significantly increased relative risk (RR, 1.3-2.1) of developing a new malignancy, the most frequent second cancer being a new germ-cell cancer. The exact role of modern treatment of germ-cell malignancies as an etiological factor of a subsequent cancer has not yet been defined. The relative risk of developing a new non-germ-cell cancer, however, seems especially high after intensive cytotoxic treatment.
恶性生殖细胞肿瘤治愈的患者发生新的恶性肿瘤的相对风险显著增加（相对风险，1.3 - 2.1），最常见的第二种癌症是新的生殖细胞癌。现代生殖细胞恶性肿瘤治疗作为后续癌症病因的确切作用尚未明确。然而，在接受强化细胞毒性治疗后，发生新的非生殖细胞癌的相对风险似乎特别高。
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