Schaefer K, Offermann G, von Herrath D, Asmus G, Hüfler M
J Dial. 1977;1(6):619-30. doi: 10.3109/08860227709037657.
Immunoreactive parathyroid hormone (iPTH) was measured in the serum and filtrate before, during and after hemofiltration. iPTH regularly declines during hemofiltration; one patient, investigated for a longer period, showed a normalization of iPTH serum level with this treatment. The iPTH values found in the hemofiltrate were remarkably high, a finding that could be explained by non-specific effects, by the occurrence of hormone fragments or by an increased secretion rate. At any rate, the results suggest a filtration of parathyroid hormone and/or hormone fragments. On the other hand, it was impossible to detect any 25-OH-vitamin D in the hemofiltrate. Finally, digoxin could be found in the filtrate, but only in very low concentrations.
在血液滤过前、滤过期间及滤过后测定血清和滤液中的免疫反应性甲状旁腺激素（iPTH）。血液滤过期间iPTH通常会下降；一名接受较长时间研究的患者经此治疗后iPTH血清水平恢复正常。血液滤过液中发现的iPTH值非常高，这一发现可通过非特异性效应、激素片段的出现或分泌率增加来解释。无论如何，结果提示甲状旁腺激素和/或激素片段可被滤过。另一方面，在血液滤过液中未检测到任何25-羟基维生素D。最后，在滤液中可检测到地高辛，但浓度极低。
