Tsutsumi M, Fukase M, Fujita T, Fujita K, Inoue S, Shin J
Miner Electrolyte Metab. 1982 Mar;7(3):146-50.
Plasma filtrate of uremic patients concentrated and fractionated by gel filtration consisted of a large peak with C-terminal immunoreactivity and a small peak with N-terminal immunoreactivity. Further analysis of the first peak with C-terminal immunoreactivity by ion exchange chromatography revealed at least 3 peaks indicating the presence of three peaks with a similar immunological behavior but different charge. The elution profile in a patient under chronic hemofiltration was different in pattern compared with that in 2 patients under conventional hemodialysis.
通过凝胶过滤浓缩和分级分离的尿毒症患者血浆滤液由一个具有C端免疫反应性的大峰和一个具有N端免疫反应性的小峰组成。通过离子交换色谱对第一个具有C端免疫反应性的峰进行进一步分析，发现至少有3个峰，表明存在三个具有相似免疫行为但电荷不同的峰。与2例接受传统血液透析的患者相比，1例接受慢性血液滤过的患者的洗脱图谱在模式上有所不同。
