Fuchs C, Doht B, Dorn D, McIntosh C, Ritter D, Scheler F
J Dial. 1977;1(6):631-40. doi: 10.3109/08860227709037658.
The acute changes in calcium, phosphate and parathyroid hormone have been examined in chronic renal failure patients under-going hemofiltration therapy and the results compared to a similar group treated by hemodialysis. In both groups there was a significant increase in Catot (0.32 mEq/1 for hemodialysis; 0.56 m Eq/1 for hemofiltration) with Ca++ remaining constant. Plasma phosphate and parathyroid hormone decreased during hemofiltration. Calcium balances were slightly positive and phosphate balances distinctly negative in all cases. To date there is no indication of induced osteodystrophy during hemofiltration therapy, although long-term studies are needed. However, the present results indicate, that hemofiltration more closely approaches the physiological situation than conventional hemodialysis.
对接受血液滤过治疗的慢性肾衰竭患者的钙、磷和甲状旁腺激素的急性变化进行了检测，并将结果与接受血液透析治疗的类似组进行了比较。两组患者的总钙（Catot）均显著升高（血液透析组为0.32 mEq/1；血液滤过组为0.56 mEq/1），而钙离子（Ca++）保持不变。血液滤过期间血浆磷和甲状旁腺激素降低。所有病例的钙平衡略为正值，磷平衡明显为负值。迄今为止，尽管需要进行长期研究，但尚无血液滤过治疗期间诱发骨营养不良的迹象。然而，目前的结果表明，与传统血液透析相比，血液滤过更接近生理状态。
