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爱泼斯坦-巴尔病毒在腮腺中的持续存在。

Persistence of Epstein-Barr virus in the parotid gland.

作者信息

Wolf H, Haus M, Wilmes E

出版信息

J Virol. 1984 Sep;51(3):795-8. doi: 10.1128/JVI.51.3.795-798.1984.

DOI:10.1128/JVI.51.3.795-798.1984
PMID:6088802
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC255846/
Abstract

Two independent techniques, in situ hybridization on frozen sections and reassociation kinetics, have been used to localize Epstein-Barr virus genomes in tissue samples from healthy human adults. Whereas specimens taken from the palatine tonsils were invariably negative, all samples from the parotid gland were positive when tested with either technique. This observation suggests that the parotid gland is, besides the peripheral lymphocytes, a site of lifelong persistence of Epstein-Barr virus and probably the site of low-level virus production which may be the source of virus found in the oropharynx.

摘要

两种独立的技术,即冷冻切片原位杂交和复性动力学,已被用于在健康成人的组织样本中定位爱泼斯坦-巴尔病毒基因组。取自腭扁桃体的标本始终呈阴性,而用这两种技术检测时,来自腮腺的所有样本均呈阳性。这一观察结果表明,除了外周淋巴细胞外,腮腺是爱泼斯坦-巴尔病毒终身持续存在的部位,可能也是低水平病毒产生的部位,而低水平病毒产生可能是口咽部发现的病毒来源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d70d/255846/1074bfc2c680/jvirol00132-0234-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d70d/255846/1074bfc2c680/jvirol00132-0234-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d70d/255846/1074bfc2c680/jvirol00132-0234-a.jpg

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1
Persistence of Epstein-Barr virus in the parotid gland.爱泼斯坦-巴尔病毒在腮腺中的持续存在。
J Virol. 1984 Sep;51(3):795-8. doi: 10.1128/JVI.51.3.795-798.1984.
2
[Evidence for the persistence of Epstein-Barr-virus in the parotid gland (author's transl)].
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3
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Cell cycle analysis of Epstein-Barr virus-infected cells following treatment with lytic cycle-inducing agents.用裂解周期诱导剂处理后,对爱泼斯坦-巴尔病毒感染细胞进行细胞周期分析。
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Kaposi's sarcoma-associated herpesvirus can productively infect primary human keratinocytes and alter their growth properties.卡波西肉瘤相关疱疹病毒可有效感染原代人角质形成细胞并改变其生长特性。
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Surface markers on human B and T lymphocytes. II. Presence of Epstein-Barr virus receptors on B lymphocytes.人类B淋巴细胞和T淋巴细胞的表面标志物。II. B淋巴细胞上爱泼斯坦-巴尔病毒受体的存在
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