Nye P C, Powell F L
Respir Physiol. 1984 Jun;56(3):369-84. doi: 10.1016/0034-5687(84)90071-9.
The steady-state discharge of fourteen arterial chemoreceptor preparations were recorded from the left cervical vagi of unidirectionally ventilated, pentobarbitone anaesthetized ducks. All were excited by both hypoxia and hypercapnia and these stimuli interacted multiplicatively, as they do in mammals. We located the receptive fields of three preparations by observing their responses to i.v. injections of 2,4-dinitrophenol before, during and after occlusion of various arteries. The responses of two preparations were consistent with their location in the ipsilateral carotid body, but the responses of one, containing two active fibres, suggested that its discharge originated in aortic bodies. The discharge of eleven preparations was not random, but came in short high frequency bursts. As stimulus intensity was increased by either hypoxia or hypercapnia the average number of impulses per burst decreased. We have shown that the arterial chemoreceptors of the duck are sensitive to both hypoxia and hypercapnia. Because the steady-state stimulus-response characteristics are essentially the same as those of mammals we suppose that both mammalian and avian chemoreceptors are excited by the same basic mechanism. We also show that ducks have active extra-carotid arterial chemoreceptors.
从单向通气、戊巴比妥麻醉的鸭的左颈迷走神经记录了14个动脉化学感受器制剂的稳态放电。所有这些制剂都受到低氧和高碳酸血症的刺激，并且这些刺激相互作用呈乘积关系，就像在哺乳动物中一样。我们通过观察三种制剂在阻断各种动脉之前、期间和之后对静脉注射2,4-二硝基苯酚的反应来定位其感受野。两种制剂的反应与其在同侧颈动脉体中的位置一致，但一种含有两根活动纤维的制剂的反应表明其放电起源于主动脉体。11种制剂的放电不是随机的，而是以短的高频爆发形式出现。当通过低氧或高碳酸血症增加刺激强度时，每个爆发的平均冲动数减少。我们已经表明，鸭的动脉化学感受器对低氧和高碳酸血症都敏感。因为稳态刺激-反应特性与哺乳动物基本相同，所以我们推测哺乳动物和鸟类的化学感受器是由相同的基本机制激发的。我们还表明，鸭具有活跃的颈外动脉化学感受器。
