Guliaeva N V, Levshina I P
Zh Vyssh Nerv Deiat Im I P Pavlova. 1984 May-Jun;34(3):554-9.
Changes of vegetative reactions and cytochrome oxidase (CChO) activity in various brain structures were studied in rats during neurotization. One week neurotization led to an increase of arterial blood pressure, respiration rate, cardiac stroke volume and heart rate. In three weeks of neurotization there was a decrease of stroke volume accompanied by an increase of heart rate and some decrease or respiration rate leading to a reduction of oxygen consumption. Neurotization during one and especially three weeks elicited an enhancement of CChO activity in various brain areas, more pronounced in the cerebral cortex. A four week "rest" after neurotization during three weeks normalized the CChO activity. CChO activation during neurotization is supposed to be one of the mechanisms of adaptation to hypoxia accompanying neurosis.
在神经移植过程中，对大鼠不同脑结构中的植物性反应和细胞色素氧化酶（CChO）活性变化进行了研究。一周的神经移植导致动脉血压、呼吸频率、心搏量和心率增加。在神经移植三周时，心搏量减少，同时心率增加，呼吸频率有所下降，导致耗氧量降低。在神经移植一周尤其是三周时，不同脑区的CChO活性增强，在大脑皮层更为明显。在三周的神经移植后四周“休息”，可使CChO活性恢复正常。神经移植过程中CChO的激活被认为是伴随神经症的缺氧适应机制之一。
