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[大白鼠高级神经活动神经症性障碍时脑的微循环及琥珀酸与NADH脱氢酶活性]

[The microcirculation and the succinate and NADH dehydrogenase activities of the brain in neurotic disorders of the higher nervous activity in white rats].

作者信息

Levshina I P, Aleksandrin V V, Kurochkina E V, Nozdracheva L V, Aleksandrov P N, Aĭrapetiants M G

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1995 Jul-Aug;45(4):811-6.

PMID:8540266
Abstract

A correlation was made between microcirculation and energy metabolism in the brain of 50 neurotized rats. Neurotic disorders were defined by characteristics of conditioning, arterial pressure, breathing rate and heart rate. In vivo biomicroscopy revealed modification of the state of blood vessels at rest and inverted reaction of brain pial vessels of neurotized rats to bilateral occlusion of common carotid arteries. Ratio of activities of respiratory cycle enzymes (succinate and NADH-dehydrogenases) was indicative of hypoxic state of the animals under study.

摘要

对50只神经化大鼠大脑中的微循环与能量代谢之间进行了相关性研究。通过条件反射、动脉血压、呼吸频率和心率等特征来定义神经紊乱。活体生物显微镜检查显示,神经化大鼠在静息状态下血管状态发生改变,且其脑软膜血管对双侧颈总动脉闭塞的反应倒置。呼吸循环酶(琥珀酸脱氢酶和NADH脱氢酶)活性的比值表明了所研究动物的缺氧状态。

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