Márquez A, Finol H J
Acta Neuropathol. 1984;63(4):347-50. doi: 10.1007/BF00687344.
Analysis of muscle biopsies from five patients, with no clinical evidence of neuromuscular disorders, showed the presence of membrane-bound structures containing glycogen (glycogenosomes). Occurrence of these structures within human muscle fibres has been usually considered a pathological finding, common to various types of metabolic diseases. Our results provide evidence that glycogenosomes are a normal constituent of human muscle fibre, thereby emphasizing that any relationship between glycogenosomes and a specific pathological condition should be established with great care.
对五名无神经肌肉疾病临床证据的患者的肌肉活检分析显示，存在含有糖原的膜结合结构（糖原小体）。这些结构在人类肌肉纤维中的出现通常被认为是一种病理发现，常见于各种类型的代谢疾病。我们的结果提供了证据表明糖原小体是人类肌肉纤维的正常组成部分，从而强调在糖原小体与特定病理状况之间建立任何关联时都应格外谨慎。
