Sakuramoto T, Kihara K, Kawai T
Hinyokika Kiyo. 1984 May;30(5):639-49.
The outcome of clinical therapy of testis tumor presenting with positive human chorionic gonadotropin (hCG) in our hospital is reported. Of 110 patients with adult germ cell testis tumor, 19 (17.3%) had elevated hCG levels in serum or urine. Two (3.1%) of the 65 patients with seminoma and 17 (37.8%) of the 45 non-seminoma patients had positive hCG. Chorionic elements were confirmed at primary and/or metastatic sites in 10 (52.6%) of these patients, and in not a few cases different histologic features were seen at the two sites. Many patients with chorionic elements had high hCG levels (more than 3,000 mIU/ml) in serum, while patients in whom no chorionic elements were detected had low hCG levels (below 1,000 mIU/ml). The hCG-positive group seemed to have a poor prognosis because they were mostly in an advanced stage at their first visit to the hospital, and no difference in prognosis was found between the patients with chorionic elements and those without. The advanced group had a poor prognosis irrespective of their hCG levels.
报告了我院以人绒毛膜促性腺激素（hCG）阳性为表现的睾丸肿瘤的临床治疗结果。在110例成年生殖细胞睾丸肿瘤患者中，19例（17.3%）血清或尿液中的hCG水平升高。65例精原细胞瘤患者中有2例（3.1%）hCG呈阳性，45例非精原细胞瘤患者中有17例（37.8%）hCG呈阳性。这些患者中有10例（52.6%）在原发和/或转移部位证实有绒毛膜成分，并且在不少病例中，两个部位可见不同的组织学特征。许多有绒毛膜成分的患者血清hCG水平较高（超过3000 mIU/ml），而未检测到绒毛膜成分的患者hCG水平较低（低于1000 mIU/ml）。hCG阳性组预后似乎较差，因为他们初诊时大多处于晚期，并且有绒毛膜成分的患者和没有绒毛膜成分的患者在预后方面未发现差异。晚期组无论hCG水平如何，预后都较差。
