口服地西泮、芬太尼或安慰剂后口腔外科手术患者的血浆β-内啡肽水平
Plasma beta-endorphin levels in oral surgery patients following diazepam, fentanyl or placebo.
作者信息
Hargreaves K M
出版信息
Anesth Prog. 1984 May-Jun;31(3):124-9.
Abstract
Plasma beta-endorphin, pain and anxiety were measured in patients before, during, and 1 and 3 hours following oral surgery. Diazepam and fentanyl blocked the stress induced increase in plasma beta-endorphin experienced by patients administered placebo. Moreover, intra-operative anxiety and post-operative pain appear to constitute independent and possibly equipotent stimuli for release of pituitary beta-endorphin in humans.
摘要
在口腔手术前、手术期间以及术后1小时和3小时测量患者的血浆β-内啡肽、疼痛和焦虑水平。地西泮和芬太尼可阻断给予安慰剂患者所经历的应激诱导的血浆β-内啡肽增加。此外，术中焦虑和术后疼痛似乎是促使人体垂体释放β-内啡肽的独立且可能等效的刺激因素。
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