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Further characterisation of a human monoclonal antibody to the rhesus D antigen produced in vitro.

作者信息

Crawford D H, McDougall D C, Mulholland N, Zanders E D, Tippett P, Huehns E R

出版信息

Behring Inst Mitt. 1984 May(74):55-60.

PMID:6089730
Abstract

UCH D4 is a human monoclonal antibody produced by an Epstein-Barr (EB) virus-transformed lymphoblastoid cell line. The antibody is specific for the rhesus D antigen, and is a good laboratory reagent for red blood cell typing. UCH D4 can be purified from the culture supernatant medium with the removal of all detectable DNA and infectious EB virus particles. This purified antibody will be used for in vivo assessment of its ability to prevent Rhesus disease of the newborn.

摘要

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