Jeng Y, Jeng I
Biochem Int. 1984 Jul;9(1):115-20.
Partial delipidation of very low density lipoproteins with heptane produced neutral lipid deficient particles. The ability of the resulting particles to interact with fibroblasts was drastically enhanced by this treatment. This new derivative was more active than low density lipoprotein containing only apoprotein B, suggesting that the recognition site of apoprotein E was also activated by heptane treatment. The partial delipidation procedure may be useful in determining total fibroblast recognition sites in a very low density lipoprotein or its derivatives.
用庚烷对极低密度脂蛋白进行部分脱脂处理可产生中性脂质缺乏颗粒。经此处理后，所得颗粒与成纤维细胞相互作用的能力大幅增强。这种新衍生物比仅含载脂蛋白B的低密度脂蛋白更具活性，这表明载脂蛋白E的识别位点也因庚烷处理而被激活。部分脱脂程序可能有助于确定极低密度脂蛋白或其衍生物中的成纤维细胞总识别位点。
