Eggers H J
Immun Infekt. 1984 Aug;12(4):187-91.
For immunocompromised patients virus infections represent a definite risk, particularly infections with measles virus and viruses of the herpes group (primary infections or reactivations). Vidarabine, acyclovir and bromovinyldeoxyuridine are therapeutically active against varicella, zoster, and herpes simplex, provided they are administered early in the course of disease. For zoster at least, the efficacy of interferon has been documented in controlled studies. No convincing therapy is so far available for the severe cytomegalovirus infections. Interferons obtained with DNA recombinant techniques are of significant promise in the near future.
对于免疫功能低下的患者,病毒感染是一种明确的风险,尤其是麻疹病毒和疱疹病毒组的病毒感染(原发性感染或再激活)。阿糖腺苷、阿昔洛韦和溴乙烯脱氧尿苷对水痘、带状疱疹和单纯疱疹具有治疗活性,前提是在疾病过程中早期早期早期给药。至少对于带状疱疹,干扰素的疗效已在对照研究中得到证实。迄今为止,对于严重的巨细胞病毒感染尚无令人信服的治疗方法。采用DNA重组技术获得的干扰素在不久的将来具有重大前景。