大鼠肺泡巨噬细胞等密度级分的功能异质性。
Functional heterogeneity of isopycnic fractions of rat alveolar macrophages.
作者信息
O'Neill S J, Hoehn S K, Lesperance E, Klass D J
出版信息
Infect Immun. 1984 Oct;46(1):282-4. doi: 10.1128/iai.46.1.282-284.1984.
Abstract
Rat alveolar macrophages separated into four isopycnic fractions on Percoll gradients were functionally heterogeneous in bacterial phagocytosis, intracellular killing, superoxide anion release, and lysosomal enzyme activity but not in hydrogen peroxide release. With increasing alveolar macrophage density, phagocytosis, intracellular killing, superoxide anion release, and lysozyme activity increase, and acid hydrolase activity decreases.
摘要
在Percoll梯度上分离成四个等密度组分的大鼠肺泡巨噬细胞，在细菌吞噬、细胞内杀伤、超氧阴离子释放和溶酶体酶活性方面功能异质性，但在过氧化氢释放方面并非如此。随着肺泡巨噬细胞密度增加，吞噬作用、细胞内杀伤、超氧阴离子释放和溶菌酶活性增加，而酸性水解酶活性降低。
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