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转座子Tn3插入大肠杆菌嵌合R/Ent质粒pCG86复制控制基因的高发生率。

High incidence of transposon Tn3 insertions into a replication control gene of the chimeric R/Ent plasmid pCG86 of Escherichia coli.

作者信息

Picken R N, Mazaitis A J, Maas W K

出版信息

J Bacteriol. 1984 Oct;160(1):430-3. doi: 10.1128/jb.160.1.430-433.1984.

DOI:10.1128/jb.160.1.430-433.1984
PMID:6090431
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC214737/
Abstract

Insertion of transposon Tn3 into the chimeric R/Ent plasmid pCG86 occurred preferentially into a replication control gene, generating mutants with increased plasmid copy number. In two mutants, the nucleotide sequence of the region of the gene containing the Tn3 insertion was determined.

摘要

转座子Tn3插入嵌合的R/Ent质粒pCG86时,优先插入到一个复制控制基因中,产生了质粒拷贝数增加的突变体。在两个突变体中,测定了含有Tn3插入的基因区域的核苷酸序列。

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High incidence of transposon Tn3 insertions into a replication control gene of the chimeric R/Ent plasmid pCG86 of Escherichia coli.转座子Tn3插入大肠杆菌嵌合R/Ent质粒pCG86复制控制基因的高发生率。
J Bacteriol. 1984 Oct;160(1):430-3. doi: 10.1128/jb.160.1.430-433.1984.
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引用本文的文献

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Nucleotide sequence analysis of RepFIC, a basic replicon present in IncFI plasmids P307 and F, and its relation to the RepA replicon of IncFII plasmids.IncFI 质粒 P307 和 F 中存在的基本复制子 RepFIC 的核苷酸序列分析及其与 IncFII 质粒 RepA 复制子的关系。
J Bacteriol. 1987 May;169(5):1836-46. doi: 10.1128/jb.169.5.1836-1846.1987.

本文引用的文献

1
Inheritance functions of group IncFII transmissible antibiotic resistance plasmids.IncFII 组可传递抗生素耐药质粒的遗传功能
Plasmid. 1981 Jan;5(1):53-75. doi: 10.1016/0147-619x(81)90077-9.
2
Genes and sites involved in replication and incompatibility of an R100 plasmid derivative based on nucleotide sequence analysis.基于核苷酸序列分析的R100质粒衍生物复制与不相容性相关的基因和位点
Mol Gen Genet. 1980;179(3):527-37. doi: 10.1007/BF00271742.
3
Cellular location of heat-labile enterotoxin in Escherichia coli.大肠杆菌中不耐热肠毒素的细胞定位
J Bacteriol. 1984 Feb;157(2):637-42. doi: 10.1128/jb.157.2.637-642.1984.
4
Nucleotide sequence of the gene for heat-stable enterotoxin II of Escherichia coli.大肠杆菌热稳定肠毒素II基因的核苷酸序列。
Infect Immun. 1983 Oct;42(1):269-75. doi: 10.1128/iai.42.1.269-275.1983.
5
Restriction enzyme maps of the chimeric R/Ent plasmid pCG86 and the related ent plasmid P307.
Plasmid. 1984 Jan;11(1):102-4. doi: 10.1016/0147-619x(84)90014-3.
6
Analysis of plasmid genome evolution based on nucleotide-sequence comparison of two related plasmids of Escherichia coli.基于大肠杆菌两个相关质粒核苷酸序列比较的质粒基因组进化分析。
Gene. 1982 Mar;17(3):299-310. doi: 10.1016/0378-1119(82)90146-9.
7
Isolation and characterization of new copy mutants of plasmid R1, and identification of a polypeptide involved in copy number control.
Mol Gen Genet. 1981;181(1):123-30. doi: 10.1007/BF00339015.
8
Structure of a naturally occurring plasmid with genes for enterotoxin production and drug resistance.一种具有产肠毒素基因和耐药性基因的天然存在质粒的结构。
J Bacteriol. 1981 Jan;145(1):97-105. doi: 10.1128/jb.145.1.97-105.1981.
9
Translocation specificity of the Tn3 element: characterization of sites of multiple insertions.Tn3元件的易位特异性:多个插入位点的特征分析
Cell. 1980 Jan;19(1):151-60. doi: 10.1016/0092-8674(80)90396-7.
10
DNA sequence analysis of the transposon Tn3: three genes and three sites involved in transposition of Tn3.转座子Tn3的DNA序列分析:与Tn3转座相关的三个基因和三个位点
Cell. 1979 Dec;18(4):1153-63. doi: 10.1016/0092-8674(79)90228-9.