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发情周期中视前区分离神经元多巴胺敏感性的变化。

Changes in dopamine sensitivity in isolated neurons of the preoptic region during the estrous cycle.

作者信息

Babichev V N

出版信息

Neurosci Behav Physiol. 1984 Sep-Oct;14(5):380-4. doi: 10.1007/BF01184607.

DOI:10.1007/BF01184607
PMID:6090981
Abstract

The dopamine sensitivity of individual neurons of the midbrain preoptic region as a center of the cyclic regulation of hypophyseal gonadotropic function was investigated under conditions of dopamine microiontophoretic delivery during various stages of the estrous cycle in rats. It was shown that most neurons do not respond to dopamine during the diestrus-1 stage. The first half of the day of the diestrus-2 stage was characterized by a high representation of neurons with an activation response. Cells with an inhibitory response to dopamine were observed to increase among the spontaneously active neurons of the preoptic region starting from the second half of the day of this stage of the estrous cycle. The greatest quantity of neurons with an inhibitory response was observed during proestrus.

摘要

作为垂体促性腺功能周期性调节中心的中脑视前区单个神经元的多巴胺敏感性,在大鼠发情周期不同阶段多巴胺微量离子导入的条件下进行了研究。结果表明,大多数神经元在动情间期-1阶段对多巴胺无反应。动情间期-2阶段的上午,具有激活反应的神经元占比很高。从发情周期该阶段的下午开始,视前区自发活动的神经元中对多巴胺有抑制反应的细胞增多。在发情前期观察到具有抑制反应的神经元数量最多。

相似文献

1
Changes in dopamine sensitivity in isolated neurons of the preoptic region during the estrous cycle.发情周期中视前区分离神经元多巴胺敏感性的变化。
Neurosci Behav Physiol. 1984 Sep-Oct;14(5):380-4. doi: 10.1007/BF01184607.
2
Unit activity in the hypothalamic arcuate area in rats at different stages of the estrous cycle.
Neurosci Behav Physiol. 1978 Jan-Mar;9(1):54-9. doi: 10.1007/BF01182656.
3
[Dynamics of dopamine-sensitivity of individual neurons in the preoptic area during the estrous cycle].
Fiziol Zh SSSR Im I M Sechenova. 1982 Mar;68(3):331-6.
4
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Fiziol Zh SSSR Im I M Sechenova. 1980 Mar;66(3):333-8.
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Reaction of neurons of arcuate region of hypothalamus to microiontophoretic application of serotonin at different stages of the estrous cycle in rats.大鼠发情周期不同阶段下丘脑弓状区域神经元对5-羟色胺微量离子电泳应用的反应。
Neurosci Behav Physiol. 1986 Jan-Feb;16(1):12-6. doi: 10.1007/BF01186883.
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[Dopamine sensitive neurons of the arcuate region of the hypothalamus and their role in regulating the gonadotropic function of the pituitary].
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Inhibition by melatonin of dopamine release from rat hypothalamus in vitro: variations with sex and the estrous cycle.褪黑素对大鼠下丘脑多巴胺体外释放的抑制作用:性别和发情周期的变化
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[Effect of beta-endorphin on preoptic region neuronal activity as the center of gonadotropic function regulation].
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