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A neurological evaluation of purported cases of SMON in Sweden.

作者信息

Gilland O

出版信息

Acta Neurol Scand Suppl. 1984;100:165-9.

PMID:6091395
Abstract

Forty Swedish victims of halogenated hydroxyquinoline neurotoxicity were claimed by Dr Hansson in 1981. He had seen only a few of these patients himself. Furthermore, in half the number of patients a neurological examination had been performed only long ago or not at all. A survey of these cases has never been presented. Therefore, extensive and, where possible, complete medical data were obtained for these 40 and one additional patient. A neurological differential diagnostic evaluation was made in each case. It was found that only one had a full-blown SMON syndrome. In all, only half of the patients in this series showed any evidence of a neurotoxic lesion due to clioquinol. The case stories were also presented in detail to the Baumgartner group, with similar diagnostic results. Detailed clinical data and differential diagnoses are presented in the communication.

摘要

相似文献

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引用本文的文献

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Founder genetic variants of ABCC4 and ABCC11 in the Japanese population are not associated with the development of subacute myelo-optico-neuropathy (SMON).在日本人群中,ABCC4 和 ABCC11 的致病变异与亚急性脊髓视神经病(SMON)的发展无关。
Mol Genet Genomic Med. 2022 Jan;10(1):e1845. doi: 10.1002/mgg3.1845. Epub 2021 Dec 24.
2
Combination treatment with fasudil and clioquinol produces synergistic anti-tumor effects in U87 glioblastoma cells by activating apoptosis and autophagy.法舒地尔和氯碘羟喹联合治疗通过激活凋亡和自噬对U87胶质母细胞瘤细胞产生协同抗肿瘤作用。
J Neurooncol. 2016 Apr;127(2):261-70. doi: 10.1007/s11060-015-2044-2. Epub 2016 Jan 2.
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Clioquinol: review of its mechanisms of action and clinical uses in neurodegenerative disorders.
弹性氨喹啉:作用机制及在神经退行性疾病中的临床应用综述。
CNS Neurosci Ther. 2012 Jan;18(1):41-6. doi: 10.1111/j.1755-5949.2010.00231.x. Epub 2010 Dec 27.