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系统性红斑狼疮患者人巨细胞病毒全身感染的免疫荧光研究

An immunofluorescent study of generalized infection of human cytomegalovirus in a patient with systemic lupus erythematosus.

作者信息

Iwasaki T, Satodate R, Masuda T, Kurata T, Hondo R

出版信息

Acta Pathol Jpn. 1984 Jul;34(4):869-74. doi: 10.1111/j.1440-1827.1984.tb07616.x.

DOI:10.1111/j.1440-1827.1984.tb07616.x
PMID:6091403
Abstract

An autopsy case of generalized infection of cytomegalovirus (CMV) in an adult with systemic lupus erythematosus is reported. CMV infection was histologically diagnosed postmortem by the presence of the characteristic cytomegalic cells with inclusion body. In the lungs, viral antigen was seen not only in the cytomegalic cells with inclusion body but also in the cells without intranuclear inclusion body in both of the frozen and the formalin-fixed paraffin sections. Viral antigen was also detected in frozen sections of the liver. CMV was isolated from the lung and liver.

摘要

报告了一例患有系统性红斑狼疮的成人巨细胞病毒(CMV)全身感染的尸检病例。通过存在带有包涵体的特征性巨细胞在组织学上进行了死后CMV感染诊断。在肺中,不仅在带有包涵体的巨细胞中,而且在冷冻切片和福尔马林固定石蜡切片中无核内包涵体的细胞中均可见病毒抗原。在肝脏的冷冻切片中也检测到病毒抗原。CMV从肺和肝脏中分离出来。

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