Gazarian K G, Nabirochkin S D, Shakhbazian A K, Shibanova E N, Tikhoneko T I
Genetika. 1984 Aug;20(8):1237-43.
RNA-containing Raus sarcoma virus, recombinant plasmid pBR322 inserted by kDNA RSV (pPrC11) and Sa7 adenovirus DNA were injected into the polar region of Drosophila melanogaster early embryons. The exogenic genetic material injected was shown to induce mutations, many of them unstable. In a number of cases, virus-specific sequences were found in DNA isolated from mutant flies. It is hypothesized that mutations induced by DNA of oncogenic viruses are of the insertion type.
