Beard C M, Benson R C, Kelalis P P, Elveback L R, Kurland L T
Mayo Clin Proc. 1977 Jan;52(1):3-7.
A population-based study of mumps orchitis over a 40-year period in Rochester, Minnesota, is reported. All medical records for patients with orchitis, atrophic testis, parotitis, and diagnosed or suspected mumps for the population of Rochester were reviewed, and detailed abstracts were prepared for all those with mumps orchitis. Information abstracted included the relationship of testicular to parotid involvement, the presence of unilateral or bilateral testicular involvement and subsequent atrophy, the presence of other complications of mumps, the treatment of mumps orchitis, and the presence of other major diagnoses. Also investigated was the number of subsequent congenital malformations in male offspring of these patients. The age distribution of the patients with orchitis (median age, 29 years) differed appreciably from those with mumps (median age, 8 years). There was no apparent increase in genitourinary malformations in the male offspring conceived after the occurrence of mumps orchitis in the fathers. Of the 132 men who had orchitis, 2 subsequently had testicular neoplasms. Both of these patients were in the group of 47 who were noted to have an atrophic testis after the occurrence of orchitis.
本文报告了一项在明尼苏达州罗切斯特市开展的为期40年的基于人群的流行性腮腺炎睾丸炎研究。回顾了罗切斯特市人群中睾丸炎、睾丸萎缩、腮腺炎以及确诊或疑似腮腺炎患者的所有医疗记录，并为所有患有腮腺炎睾丸炎的患者编写了详细摘要。提取的信息包括睾丸受累与腮腺受累的关系、单侧或双侧睾丸受累及随后萎缩的情况、腮腺炎其他并发症的存在情况、腮腺炎睾丸炎的治疗情况以及其他主要诊断的存在情况。还调查了这些患者男性后代中后续先天性畸形的数量。睾丸炎患者的年龄分布（中位年龄29岁）与腮腺炎患者（中位年龄8岁）明显不同。父亲患腮腺炎睾丸炎后受孕的男性后代中，泌尿生殖系统畸形没有明显增加。在132名患有睾丸炎的男性中，有2人随后患了睾丸肿瘤。这两名患者均在睾丸炎发生后被发现睾丸萎缩的47人组中。
