Pohjanpelto P, Lahdensivu R
Scand J Infect Dis. 1984;16(3):229-33. doi: 10.3109/00365548409070394.
Infectious hepatitis, based on clinical diagnosis, has been reported by practicing doctors in Finland to the National Board of Health since 1943. Two epidemics of infectious hepatitis have been recorded. The first one with more than 16000 cases occurred in 1948 and the second one in 1954-57 with a peak of more than 7000 cases in 1956. After that infectious hepatitis has declined rapidly. In 1966 only 363 cases were reported. Although the figures are incomplete they reflect the changes that have taken place in the frequency of infectious hepatitis in Finland. The statistics are supported by serological studies. 24% of the sera collected in 1970 from 20-24-yr-old Finns, born in 1946-50, contained antibodies of the IgG class to hepatitis A while only 0.3% of the sera collected in 1982-83 from the same age group, born in 1958-63, contained these antibodies. Only 3.2% of the sera sent to our laboratory for hepatitis A diagnosis in 1980-82 contained antibodies of the IgM class to hepatitis A, and at least 68% of these infections were connected with travel in foreign countries. This paper shows that the prevalence of hepatitis A is low in Finland and that a rapid decline in its frequency has taken place during the last 25 years.
自1943年起，芬兰的执业医生就根据临床诊断将感染性肝炎上报给国家卫生局。已记录了两次感染性肝炎的流行情况。第一次有超过16000例病例，发生在1948年；第二次在1954年至1957年，1956年达到高峰，超过7000例。此后，感染性肝炎迅速减少。1966年仅报告了363例。尽管数据不完整，但它们反映了芬兰感染性肝炎发病率的变化。这些统计数据得到了血清学研究的支持。1970年从1946年至1950年出生的20至24岁芬兰人采集的血清中，24%含有甲型肝炎IgG类抗体，而1982年至1983年从同一年龄组（1958年至1963年出生）采集的血清中，只有0.3%含有这些抗体。1980年至1982年送到我们实验室进行甲型肝炎诊断的血清中，只有3.2%含有甲型肝炎IgM类抗体，而且这些感染中至少68%与国外旅行有关。本文表明，芬兰甲型肝炎的流行率较低，并且在过去25年中其发病率迅速下降。
