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[中枢神经系统疱疹性病变的诊断]

[Diagnosis of herpetic lesions of the central nervous system].

作者信息

Kogan I L, Aksenov O A, Zinchenko A P, Sorokina M N

出版信息

Vopr Virusol. 1984 Jul-Aug;29(4):441-7.

PMID:6093385
Abstract

The results of the use of the two new methods for early diagnosis of herpes simplex virus infection based on immuno-mediated hemagglutination and hemadsorption are presented. In these methods, staphylococcal diagnostic preparations with two kinds of adsorbed antibody are used which allow the presence of the virus to be detected and simultaneously identified. These tests help to detect virus both in the liquid phase at 1-8 days after the onset of the study (immune competition test) and in infected culture cells within the first few days postinfection and long before the appearance of marked cytopathic effect (immune hemadsorption tect). The employment of these methods for the diagnosis of herpetic affection of the central nervous system in children increases by 10-15% the rate of detection of herpes simplex virus with simultaneous identification of the virus.

摘要

本文介绍了基于免疫介导血凝和血吸附的两种单纯疱疹病毒感染早期诊断新方法的应用结果。在这些方法中,使用了带有两种吸附抗体的葡萄球菌诊断制剂,可检测并同时鉴定病毒的存在。这些检测方法有助于在研究开始后1 - 8天的液相中(免疫竞争试验)以及感染后最初几天且远在明显细胞病变效应出现之前的感染培养细胞中(免疫血吸附试验)检测病毒。将这些方法用于诊断儿童中枢神经系统疱疹感染时,单纯疱疹病毒的检测率提高了10 - 15%,同时可对病毒进行鉴定。

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