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盐酸可乐定用于美沙酮治疗脱毒——纳曲酮后续护理的价值。

Clonidine hydrochloride detoxification from methadone treatment--the value of naltrexone aftercare.

作者信息

Rawson R A, Washton A M, Resnick R B, Tennant F S

出版信息

Adv Alcohol Subst Abuse. 1984 Spring;3(3):41-9. doi: 10.1300/J251v03n03_04.

DOI:10.1300/J251v03n03_04
PMID:6093484
Abstract

Treatment outcomes were compared for 2 groups of subjects detoxified from methadone using clonidine. One group of 12 subjects was encouraged to continue in treatment with naltrexone, while the other 12 subjects did not have naltrexone treatment available. Results suggested that those subjects who had naltrexone available were more successful at completing the 10 day detoxification treatment and that the relapse rate at 30 days post-treatment was significantly reduced by naltrexone treatment.

摘要

对两组使用可乐定进行美沙酮脱毒治疗的受试者的治疗结果进行了比较。一组12名受试者被鼓励继续接受纳曲酮治疗,而另一组12名受试者没有接受纳曲酮治疗。结果表明,那些可以使用纳曲酮的受试者在完成10天脱毒治疗方面更成功,并且纳曲酮治疗显著降低了治疗后30天的复发率。

相似文献

1
Clonidine hydrochloride detoxification from methadone treatment--the value of naltrexone aftercare.盐酸可乐定用于美沙酮治疗脱毒——纳曲酮后续护理的价值。
Adv Alcohol Subst Abuse. 1984 Spring;3(3):41-9. doi: 10.1300/J251v03n03_04.
2
The sequential use of clonidine and naltrexone in the treatment of opiate addicts.可乐定与纳曲酮序贯用于阿片类成瘾者的治疗。
Adv Alcohol Subst Abuse. 1984 Spring;3(3):19-39. doi: 10.1300/J251v03n03_03.
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Clonidine hydrochloride detoxification from methadone treatments: the value of naltrexone aftercare.美沙酮治疗中盐酸可乐定脱毒:纳曲酮后续护理的价值。
NIDA Res Monogr. 1981 Feb;34:101-8.
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Clonidine and naltrexone. A safe, effective, and rapid treatment of abrupt withdrawal from methadone therapy.
Arch Gen Psychiatry. 1982 Nov;39(11):1327-32. doi: 10.1001/archpsyc.1982.04290110077013.
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The role of the National Institute on Drug Abuse in the development of naltrexone.美国国家药物滥用研究所(National Institute on Drug Abuse)在纳曲酮研发中的作用。
J Clin Psychiatry. 1984 Sep;45(9 Pt 2):4-6.
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[Clonidine-naltrexone: a new technic for the detoxification of opiate addicts].可乐定-纳曲酮:一种用于阿片类成瘾者戒毒的新技术
Med Clin (Barc). 1990 Nov 10;95(16):627-9.
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Opiate addiction and the locus coeruleus. The clinical utility of clonidine, naltrexone, methadone, and buprenorphine.阿片类药物成瘾与蓝斑核。可乐定、纳曲酮、美沙酮和丁丙诺啡的临床应用。
Psychiatr Clin North Am. 1993 Mar;16(1):61-73.
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Effectiveness of low-dose naltrexone in the post-detoxification treatment of opioid dependence.低剂量纳曲酮在阿片类药物依赖脱毒后治疗中的有效性。
J Clin Psychopharmacol. 2007 Oct;27(5):468-74. doi: 10.1097/jcp.0b013e31814e5e9d.
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Clonidine hydrochloride: a nonopiate treatment for opiate withdrawal.
NIDA Res Monogr. 1979;27:233-9.
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In-patient detoxification procedures, treatment retention, and post-treatment opiate use: comparison of lofexidine + naloxone, lofexidine + placebo, and methadone.住院戒毒程序、治疗留存率及治疗后阿片类药物使用情况:洛非西定+纳洛酮、洛非西定+安慰剂与美沙酮的比较
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引用本文的文献

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Naltrexone. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in the management of opioid dependence.纳曲酮。对其药效学和药代动力学特性以及在阿片类药物依赖管理中的治疗效果的综述。
Drugs. 1988 Mar;35(3):192-213. doi: 10.2165/00003495-198835030-00002.