Turco D
Ann Osp Maria Vittoria Torino. 1983 Jul-Dec;26(7-12):326-39.
A brief account of the most frequently observed side-effects of the protracted administration of oestroprogestinic substances is followed by a detailed explanation of the damage they may cause to the hepatobiliary apparatus: cholestatic icterus; cholesterolic biliary lithiasis; benign and malignant liver neoplasias. Reference is made to the liver diagnosis problems the practitioner may encounter when dealing with patients treated with these substances. Stress is laid on the need for close monitoring of tolerance and the possible effects of oestroprogestinic management on liver and bile function.
在简要介绍了长期服用雌激素 - 孕激素类物质最常见的副作用之后,详细解释了它们可能对肝胆系统造成的损害:胆汁淤积性黄疸;胆固醇性胆石症;肝脏良性和恶性肿瘤。文中提到了医生在治疗使用这些物质的患者时可能遇到的肝脏诊断问题。强调了密切监测耐受性以及雌激素 - 孕激素治疗对肝脏和胆汁功能可能产生的影响的必要性。