Sow A
J Antimicrob Chemother. 1984 Sep;14 Suppl B:191-4. doi: 10.1093/jac/14.suppl_b.191.
Dangerous in all circumstances, purulent meningitis is even more life-threatening in tropical areas. This results from underlying malnutrition, haemoglobinopathy and enzymopathy, but also from delays in treatment. We have treated 28 patients, 16 boys and 12 girls, aged from 16 days to 7 years suffering from purulent meningitis, with cefotaxime. Almost half of the patients were suffering from malnutrition and low body weight, or from haemoglobinopathy. Cefotaxime, administered 2 or 3 times daily intramuscularly, was given at 90 to 200/mg/kg with a mean of 150/mg/kg/day. Overall, results showed a 79% cure rate including 71% complete recovery, the highest ever seen in the department.
在任何情况下，化脓性脑膜炎都很危险，在热带地区更是危及生命。这是由潜在的营养不良、血红蛋白病和酶病导致的，同时也归因于治疗延误。我们用头孢噻肟治疗了28例化脓性脑膜炎患者，其中16名男孩，12名女孩，年龄从16天至7岁。几乎一半的患者患有营养不良、体重过轻或血红蛋白病。头孢噻肟每日肌内注射2至3次，剂量为90至200毫克/千克，平均剂量为150毫克/千克/天。总体而言，治疗结果显示治愈率为79%，其中71%完全康复，这是该科室有史以来的最高治愈率。
