Tancrede C H, Andremont A O, Leonard F C
J Antimicrob Chemother. 1984 Sep;14 Suppl B:53-7. doi: 10.1093/jac/14.suppl_b.53.
Cefotaxime treatment eliminates normally susceptible strains of enterobacteria from the digestive tract, and increases intestinal carriage of resistant enterobacteria in individuals. However the global rate of such carriage remains low in hospitalized patients and resistant strains are exceptionally isolated from bacteraemia in spite of an intensive use of this antibiotic. The epidemiology of resistant strains of enterobacteria has to be carefully monitored. The results obtained by the control of faecal carriage shows that this technique is a means of surveying evolution in this area.
头孢噻肟治疗可消除消化道中通常敏感的肠杆菌菌株,并增加个体肠道中耐药肠杆菌的携带率。然而,在住院患者中,这种携带的总体发生率仍然较低,尽管这种抗生素被大量使用,但耐药菌株从菌血症中被分离出来的情况极为罕见。必须仔细监测肠杆菌耐药菌株的流行病学情况。通过控制粪便携带情况获得的结果表明,这项技术是一种监测该领域演变的手段。