重症监护病房中产超广谱β-内酰胺酶肠杆菌科细菌定植与感染的前瞻性调查
Prospective survey of colonization and infection caused by expanded-spectrum-beta-lactamase-producing members of the family Enterobacteriaceae in an intensive care unit.
作者信息
De Champs C, Sauvant M P, Chanal C, Sirot D, Gazuy N, Malhuret R, Baguet J C, Sirot J
机构信息
Laboratoire de Bactériologie-Virologie-Hygiène, Faculté de Médecine, France.
出版信息
J Clin Microbiol. 1989 Dec;27(12):2887-90. doi: 10.1128/jcm.27.12.2887-2890.1989.
Abstract
The occurrence of expanded-spectrum-beta-lactamase-producing strains was prospectively studied in 56 patients in an intensive care unit. Ten patients were infected or colonized; some of these patients had asymptomatic intestinal colonization. Four different expanded-spectrum beta-lactamases were identified and used as epidemiological markers to survey nosocomial infections.
摘要
对重症监护病房的56例患者进行前瞻性研究，以观察产超广谱β-内酰胺酶菌株的出现情况。10例患者受到感染或出现定植；其中一些患者有无症状肠道定植。鉴定出四种不同的超广谱β-内酰胺酶，并将其用作监测医院感染的流行病学标志物。
相似文献
1
Prospective survey of colonization and infection caused by expanded-spectrum-beta-lactamase-producing members of the family Enterobacteriaceae in an intensive care unit.重症监护病房中产超广谱β-内酰胺酶肠杆菌科细菌定植与感染的前瞻性调查
J Clin Microbiol. 1989 Dec;27(12):2887-90. doi: 10.1128/jcm.27.12.2887-2890.1989.
2
Fecal carriage and intrafamilial spread of extended-spectrum β-lactamase-producing enterobacteriaceae following colonization at the neonatal ICU.新生儿重症监护病房定植后，产超广谱β-内酰胺酶肠杆菌科在粪便中的携带和家庭内传播。
Pediatr Crit Care Med. 2013 Feb;14(2):157-63. doi: 10.1097/PCC.0b013e31824ea2a2.
3
ICU Acquisition Rate, Risk Factors, and Clinical Significance of Digestive Tract Colonization With Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae: A Systematic Review and Meta-Analysis.重症监护病房获得性产超广谱β-内酰胺酶肠杆菌科细菌消化道定植率、危险因素及临床意义：一项系统评价与Meta分析
Crit Care Med. 2017 Apr;45(4):705-714. doi: 10.1097/CCM.0000000000002253.
4
Significance of Prior Digestive Colonization With Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae in Patients With Ventilator-Associated Pneumonia.产超广谱β-内酰胺酶肠杆菌科定植对呼吸机相关性肺炎患者的意义。
Crit Care Med. 2016 Apr;44(4):699-706. doi: 10.1097/CCM.0000000000001471.
5
Intestinal Colonization by Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae in Infants.产超广谱β-内酰胺酶肠杆菌科细菌在婴儿肠道的定植
Rev Invest Clin. 2015 Sep-Oct;67(5):313-7.
6
Control of Enterobacteriaceae producing extended-spectrum beta-lactamase in intensive care units: rectal screening may not be needed in non-epidemic situations.重症监护病房中产超广谱β-内酰胺酶肠杆菌科细菌的控制：在非流行情况下可能无需进行直肠筛查。
Infect Control Hosp Epidemiol. 2004 Oct;25(10):838-41. doi: 10.1086/502305.
7
[Examination of maternal extended spectrum beta-lactamase bacterial colonization and follow-up of newborns requiring Neonatal Intensive Care Unit admission].[孕产妇产超广谱β-内酰胺酶细菌定植情况检查及入住新生儿重症监护病房新生儿的随访]
Orv Hetil. 2016 Aug;157(34):1353-6. doi: 10.1556/650.2016.30514.
8
Comparison of rates of fecal colonization with extended-spectrum beta-lactamase-producing enterobacteria among patients in different wards, outpatients and medical students.不同病房患者、门诊患者及医学生中产超广谱β-内酰胺酶肠杆菌科细菌粪便定植率的比较。
Microbiol Immunol. 2016 May;60(5):285-94. doi: 10.1111/1348-0421.12373.
9
Mother-to-child transmission of extended-spectrum-beta-lactamase-producing Enterobacteriaceae.肠杆菌科产超广谱β-内酰胺酶的母婴传播。
J Hosp Infect. 2018 Sep;100(1):40-46. doi: 10.1016/j.jhin.2017.12.024. Epub 2018 Jan 10.
10
Evaluation of a real-time PCR assay for rectal screening of OXA-48-producing Enterobacteriaceae in a general intensive care unit of an endemic hospital.在一家地方性医院的普通重症监护病房中，评估一种用于直肠筛查产OXA-48肠杆菌科细菌的实时聚合酶链反应检测方法。
Diagn Microbiol Infect Dis. 2017 Jul;88(3):252-258. doi: 10.1016/j.diagmicrobio.2017.04.001. Epub 2017 Apr 6.
引用本文的文献
1
A novel diguanylate cyclase contributes to intestinal cell adhesion, biofilm formation, iron utilization, and virulence by gastrointestinal infection.一种新型二鸟苷酸环化酶通过胃肠道感染促进肠道细胞黏附、生物膜形成、铁利用及毒力。
Virulence. 2025 Dec;16(1):2544882. doi: 10.1080/21505594.2025.2544882. Epub 2025 Aug 14.
2
Analysis of ESAC-Net/EARS-Net Data from 29 EEA Countries for Spatiotemporal Associations Between Antimicrobial Use and Resistance-Implications for Antimicrobial Stewardship?对来自29个欧洲经济区国家的ESAC-Net/EARS-Net数据进行分析，以研究抗菌药物使用与耐药性之间的时空关联——对抗菌药物管理有何启示？
Antibiotics (Basel). 2025 Apr 13;14(4):399. doi: 10.3390/antibiotics14040399.
3
Extended-Spectrum Beta-Lactamase and Carbapenem-Resistant Gram-Negative Pathogens in Makkah, Saudi Arabia.沙特麦加的产超广谱β-内酰胺酶和碳青霉烯类耐药革兰氏阴性病原菌。
Ethiop J Health Sci. 2022 Nov;32(6):1221-1230. doi: 10.4314/ejhs.v32i6.20.
4
Molecular Mechanisms and Epidemiology of Carbapenem-Resistant Complex Isolated from Chinese Patients During 2004-2018.2004年至2018年期间从中国患者中分离出的耐碳青霉烯类复合菌的分子机制与流行病学
Infect Drug Resist. 2021 Sep 7;14:3647-3658. doi: 10.2147/IDR.S327595. eCollection 2021.
5
The Great ESKAPE: Exploring the Crossroads of Bile and Antibiotic Resistance in Bacterial Pathogens.ESKAPE 之宏大：探索细菌病原体胆汁与抗生素耐药性的交汇点。
Infect Immun. 2020 Sep 18;88(10). doi: 10.1128/IAI.00865-19.
6
Complete Genome Sequence of Klebsiella pneumoniae Strain TK421, a Conjugative Hypervirulent Isolate.肺炎克雷伯菌菌株TK421（一种可接合的高毒力分离株）的全基因组序列
Microbiol Resour Announc. 2020 Jan 16;9(3):e01408-19. doi: 10.1128/MRA.01408-19.
7
spp.: Update on Taxonomy, Clinical Aspects, and Emerging Antimicrobial Resistance.spp.：分类学、临床方面和新出现的抗菌药物耐药性的最新进展。
Clin Microbiol Rev. 2019 Jul 17;32(4). doi: 10.1128/CMR.00002-19. Print 2019 Sep 18.
8
RcsB regulation of the YfdX-mediated acid stress response in Klebsiella pneumoniae CG43S3.肺炎克雷伯氏菌 CG43S3 中 RcsB 对 YfdX 介导的酸应激反应的调节。
PLoS One. 2019 Feb 28;14(2):e0212909. doi: 10.1371/journal.pone.0212909. eCollection 2019.
9
Multidrug-Resistant Complex Emerging as a Global, Diversifying Threat.多重耐药复合体正成为一种全球性、不断多样化的威胁。
Front Microbiol. 2019 Jan 31;10:44. doi: 10.3389/fmicb.2019.00044. eCollection 2019.
10
A Novel Role for the Klebsiella pneumoniae Sap (Sensitivity to Antimicrobial Peptides) Transporter in Intestinal Cell Interactions, Innate Immune Responses, Liver Abscess, and Virulence.一种新型的肺炎克雷伯菌 Sap（对抗菌肽的敏感性）转运蛋白在肠道细胞相互作用、先天免疫反应、肝脓肿和毒力中的作用。
J Infect Dis. 2019 Apr 8;219(8):1294-1306. doi: 10.1093/infdis/jiy615.
本文引用的文献
1
Influence of erythromycin on the normal human flora and colonization of the oral cavity, throat and colon.
Scand J Infect Dis. 1982;14(1):49-56. doi: 10.3109/inf.1982.14.issue-1.10.
2
Epidemiology of enterobacteria resistant to cefotaxime in hospital.医院中对头孢噻肟耐药的肠杆菌科细菌的流行病学
J Antimicrob Chemother. 1984 Sep;14 Suppl B:53-7. doi: 10.1093/jac/14.suppl_b.53.
3
Amikacin-resistant gram-negative bacilli: correlation of occurrence with amikacin use.耐阿米卡星革兰氏阴性杆菌：其发生与阿米卡星使用的相关性
J Infect Dis. 1985 Feb;151(2):295-300. doi: 10.1093/infdis/151.2.295.
4
Klebsiella pneumoniae strains more resistant to ceftazidime than to other third-generation cephalosporins.
J Antimicrob Chemother. 1987 Oct;20(4):611-2. doi: 10.1093/jac/20.4.611.
5
Transferable resistance to third-generation cephalosporins in clinical isolates of Klebsiella pneumoniae: identification of CTX-1, a novel beta-lactamase.肺炎克雷伯菌临床分离株对第三代头孢菌素的可转移耐药性：新型β-内酰胺酶CTX-1的鉴定
J Antimicrob Chemother. 1987 Sep;20(3):323-34. doi: 10.1093/jac/20.3.323.
6
Novel plasmid-mediated beta-lactamase in clinical isolates of Klebsiella pneumoniae more resistant to ceftazidime than to other broad-spectrum cephalosporins.新型质粒介导的β-内酰胺酶存在于肺炎克雷伯菌临床分离株中，这些分离株对头孢他啶的耐药性高于对其他广谱头孢菌素的耐药性。
Antimicrob Agents Chemother. 1988 May;32(5):626-30. doi: 10.1128/AAC.32.5.626.
7
Extended broad-spectrum beta-lactamases conferring transferable resistance to newer beta-lactam agents in Enterobacteriaceae: hospital prevalence and susceptibility patterns.产超广谱β-内酰胺酶导致肠杆菌科细菌对新型β-内酰胺类药物产生可转移耐药性：医院流行情况及药敏模式
Rev Infect Dis. 1988 Jul-Aug;10(4):867-78. doi: 10.1093/clinids/10.4.867.
8
Selective decontamination of the digestive tract and prevention of infection in intensive care units.重症监护病房中消化道的选择性去污与感染预防
J Antimicrob Chemother. 1988 Aug;22(2):97-101. doi: 10.1093/jac/22.2.97.
9
Comparative study of a novel plasmid-mediated beta-lactamase, CAZ-2, and the CTX-1 and CAZ-1 enzymes conferring resistance to broad-spectrum cephalosporins.新型质粒介导的β-内酰胺酶CAZ-2与赋予对广谱头孢菌素耐药性的CTX-1和CAZ-1酶的比较研究。
Antimicrob Agents Chemother. 1988 Nov;32(11):1660-5. doi: 10.1128/AAC.32.11.1660.
10
Plasmid-mediated resistance to third-generation cephalosporins caused by point mutations in TEM-type penicillinase genes.由TEM型青霉素酶基因点突变引起的质粒介导的对第三代头孢菌素的耐药性。
Rev Infect Dis. 1988 Jul-Aug;10(4):879-84. doi: 10.1093/clinids/10.4.879.
Zotero 插件