Aoyama R, Waga S, Ohnishi A, Izumi Y, Asuka N
Jpn J Antibiot. 1984 Oct;37(10):1785-7.
Clinical studies on sulbactam/cefoperazone (SBT/CPZ) were carried out and the results were as follows: Eleven patients (pneumonia 8, acute purulent arthritis of the knee joint 1, urinary tract infection 2) were treated with SBT/CPZ, in doses of 30-67 mg/kg divided 3 times per day for 3-61/3 days intravenously. The overall efficacy rate was 100%. As to adverse reaction, diarrhea was observed in 1 case. Abnormal laboratory data were noted in 2 cases (GPT elevation in 1, and eosinophilia and GPT elevation in 1).
进行了舒巴坦/头孢哌酮(SBT/CPZ)的临床研究,结果如下:11例患者(8例肺炎、1例膝关节急性化脓性关节炎、2例尿路感染)接受了SBT/CPZ治疗,剂量为30 - 67mg/kg,每日静脉注射3次,持续3 - 6 1/3天。总有效率为100%。关于不良反应,观察到1例腹泻。2例出现实验室数据异常(1例谷丙转氨酶升高,1例嗜酸性粒细胞增多及谷丙转氨酶升高)。