Peghini M, Genelle B, Reynaud J P, Monnier A, Beda Y B
Med Trop (Mars). 1984 Jul-Sep;44(3):253-7.
The rarity of cholelithiasis in black Africa is a very classical concept that must be called in question again. With the exception of pigmentary lithiasis frequently found in patients with an homozygous haemoglobinopathy, genetic as well as environmental (particularly food related) factors explain in part the low frequency of cholelithiasis with cholesterol gallstones in Africa. Yet the true incidence of cholelithiasis is too often unappreciated. Before the use of ultrasonography, only symptomatic cholelithiasis were detected, usually by the surgeon (19 cases admitted during a 6 years period in the Internal Medicine Department at Treichville University Hospital, Abidjan). The practice of ultrasonography will ease the detection of asymptomatic cholelithiasis. Since ultrasonography has been set up at Treichville University Hospital, 30 cholelithiasis of which 21 were asymptomatic have been detected during an 8 months period, a high detection level of course for a so-called rare disease.
在黑非洲地区，胆结石发病率低是一个非常经典的概念，但现在必须再次对此提出质疑。除了在纯合子血红蛋白病患者中常见的色素性结石外，遗传因素和环境因素（尤其是与食物相关的因素）在一定程度上解释了非洲胆固醇结石性胆结石发病率较低的原因。然而，胆结石的真实发病率常常未得到充分认识。在超声检查应用之前，通常只有有症状的胆结石才能被发现，一般是由外科医生发现（阿比让特雷奇维尔大学医院内科在6年期间收治了19例）。超声检查的应用将便于发现无症状胆结石。自从特雷奇维尔大学医院开展超声检查以来，在8个月的时间里发现了30例胆结石，其中21例无症状，对于一种所谓的罕见疾病来说，这当然是一个很高的检出率。
