Koreli A, Davituliani D
Physiol Behav. 1984 Aug;33(2):339-41. doi: 10.1016/0031-9384(84)90122-7.
Tranquilizers of the benzodiazepine group (oxazepam and diazepam) enhanced the rate of self-stimulation elicited from the lateral hypothalamus. Both tranquilizers induced reversal of escape and avoidance behaviors elicited from the medial hypothalamus to a high rate self-stimulation. The reversal effect persisted for two days and the initial negative emotional responses returned later as the drugs were depleted in the organisms. Thus the effect of minor tranquilizers substantially mimics the ventral hippocampus ablation effect which also produced the reversal of the medial hypothalamus responses in earlier experiments.
苯二氮䓬类镇静剂（奥沙西泮和地西泮）提高了从外侧下丘脑引发的自我刺激速率。两种镇静剂都使从中脑下丘脑引发的逃避和回避行为逆转，变为高频率的自我刺激。这种逆转效应持续了两天，随着药物在生物体中耗尽，最初的负面情绪反应后来又恢复了。因此，小剂量镇静剂的作用基本上模拟了腹侧海马体切除的效果，在早期实验中，腹侧海马体切除也产生了中脑下丘脑反应的逆转。
