Nisticò G, Faraone V, Naccari F, Ammendola D, Germanò D, Marmo E
Res Commun Chem Pathol Pharmacol. 1984 Oct;46(1):35-42.
The effects of intramuscular treatment for 3 and 5 consecutive days with thallium sulphate (2.5, 5 and 10 mg/Kg) on GABA content, glutamate - decarboxylase (GAD) and GABA-transaminase (GABA-T) activity in different areas of the rat brain were studied. Thallium at the dose levels used did not produce significant changes in GABA content, GAD and GABA-T activity in the brain hemispheres, brainstem, hypothalamus, diencephalon and caudate nucleus.
研究了连续3天和5天肌肉注射硫酸铊(2.5、5和10毫克/千克)对大鼠脑不同区域γ-氨基丁酸(GABA)含量、谷氨酸脱羧酶(GAD)和GABA转氨酶(GABA-T)活性的影响。所用剂量水平的铊未使大脑半球、脑干、下丘脑、间脑和尾状核中的GABA含量、GAD和GABA-T活性产生显著变化。