Becciolini A, Cremonini D, Fabbrica D, Balzi M
Acta Radiol Oncol. 1984;23(5):353-9. doi: 10.3109/02841868409136033.
The behaviour of qualitative and quantitative morphologic parameters in rats exposed on the abdomen only to multiple daily fractionation (MDF) of 3 Gy X 2 and 3 Gy X 2 X 2 with 12 h splits was analyzed. Both doses were sublethal. The number of epithelial cells in the crypts and in the whole formation, the mitotic index, and the labelling index appeared to be markedly reduced at early intervals after irradiation. Repair and recovery quickly led to normal morphology. The effects of an 8 Gy single dose were compared with those from multiple fractionations.
分析了仅腹部接受3 Gy×2和3 Gy×2×2、分割间隔为12小时的多次每日分割照射（MDF）的大鼠的定性和定量形态学参数的变化情况。这两种剂量均为亚致死剂量。照射后早期，隐窝及整个组织中的上皮细胞数量、有丝分裂指数和标记指数均明显降低。修复和恢复迅速使形态恢复正常。将8 Gy单次剂量的效应与多次分割照射的效应进行了比较。
