Benucci A, Becciolini A, Nardino A, Balzi M, Cremonini D, Franciolini F
Acta Radiol Oncol. 1981;20(3):193-8. doi: 10.3109/02841868109130195.
The uptake of 14C leucine administered at different intervals after irradiation, but always 4 and 8 h before the animals were killed, has been evaluated in tissues with different proliferative activity and protein synthesis. The results have demonstrated an increased uptake and a more rapid elimination of the tracer after irradiation. In the small intestine a lower amount of TCA insoluble fraction was observed when the morphologic injury was evident, while protein synthesis significantly increased during the initial phase of appearance of the injury and mainly during the recovery phase of epithelial cells. Kidney and plasma had levels higher than controls at all intervals.
在照射后不同时间间隔给予14C亮氨酸，但总是在处死动物前4小时和8小时给药，已在具有不同增殖活性和蛋白质合成的组织中评估了其摄取情况。结果表明，照射后示踪剂的摄取增加且消除更快。在小肠中，当形态学损伤明显时，观察到三氯乙酸不溶性部分的量较低，而在损伤出现的初始阶段，尤其是在上皮细胞的恢复阶段，蛋白质合成显著增加。肾脏和血浆在所有时间间隔的水平均高于对照组。
