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同性恋男性胃肠道巨细胞病毒感染的意义

Significance of gastrointestinal cytomegalovirus infection in homosexual males.

作者信息

Blackman E, Vimadalal S, Nash G

出版信息

Am J Gastroenterol. 1984 Dec;79(12):935-40.

PMID:6095652
Abstract

Gastrointestinal cytomegalovirus (CMV) infection usually occurs in immunosuppressed patients and has recently been reported in patients with the acquired immune deficiency syndrome (AIDS). Serological evidence of CMV infection and a variety of traumatic and infectious gastrointestinal disorders are known to occur in nonimmunosuppressed homosexual males. However, the significance of gastrointestinal CMV infection in nonimmunosuppressed homosexual males is not well known. Three unusual cases of gastrointestinal CMV infection in homosexual males are presented. Infection of a Kock pouch in one patient and an anal ulcer in another, occurred as part of a CMV mononucleosis syndrome. In the third patient, CMV was found in an acutely inflamed appendix. Although gastrointestinal CMV infection has been reported frequently in patients with AIDS, our patients showed no evidence of immunosuppression or AIDS 6 wk to 1 year later. Gastrointestinal CMV infection in homosexual males with gastrointestinal disease should not be considered indicative of AIDS.

摘要

胃肠道巨细胞病毒(CMV)感染通常发生在免疫抑制患者中,最近在获得性免疫缺陷综合征(AIDS)患者中也有报道。已知在非免疫抑制的同性恋男性中会出现CMV感染的血清学证据以及各种创伤性和感染性胃肠道疾病。然而,胃肠道CMV感染在非免疫抑制同性恋男性中的意义尚不清楚。本文介绍了3例同性恋男性胃肠道CMV感染的不寻常病例。1例患者的Kock贮袋感染和另1例患者的肛门溃疡,是作为CMV单核细胞增多症综合征的一部分出现的。在第3例患者中,在急性发炎的阑尾中发现了CMV。尽管AIDS患者中经常报道胃肠道CMV感染,但我们的患者在6周后至1年期间没有免疫抑制或AIDS的证据。患有胃肠道疾病的同性恋男性中的胃肠道CMV感染不应被视为AIDS的指征。

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